Material Properties

  • aesPlla® is a bio-stimulatory dermal filler injectable that contains microparticles of poly-L-lactic acid (PLLA), carboxymethylcellulose, mannitol and sterile water for injection.
  • The solution must be dissolved for 3 hours, remaining stable for 72 hours.
  • Following injection, PLLA stimulates fibroblasts to promote collagen production and restore the volume lost due to ageing.
  • PLLA is gradually broken down in the body over time, biodegrading into water and CO2.
  • aesPlla® is available in 365mg dose vials and is to be reconstituted prior to use by the addition of 5ml sterile water for injection.
  • Fox recommend using a 26G cannula or needle to inject.


  • Patients who have a history of or susceptibility to keloid formation or hypertrophic scarring.
  • Those who are allergic to any ingredient of aesPlla® : “poly-L-lactic acid” (PLLA), carboxymethylcellulose (USP) or mannitol (USP).
  • Patients who have risks factors for hypertrophic scarring or keloid formation.


  • Each vial of dry powder contains: 150mg of poly-L-lactic acid, 90mg of carboxymethylcellulose and 125mg of mannitol.
Composition Each vial of dry powder contains: 150mg of poly-L-lactic acid, 90mg of carboxymethylcellulose, 125mg of mannitol.
Recommended Indications Deep dermal deficiencies
Facial wrinkles & folds
Marionette lines
Sagging jowls
Preparation Time 3 hours
Injection Depth Inject into the deep dermis / lower layers of dermis / layers of hypodermis
Needle Size 26G blunt cannula
Duration Once initial treatment sessions are complete results will last up to 3 years.
Storage Do not refrigerate, store at room temperature.
Shelf Life 21 months from date of manufacture.


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